【摘要】 目的:探讨99Tcm-MIBIS PECT/CT异机融合断层显像对肺癌的临床诊断价值。方法:选择65例肺部占位性病变患者行99Tcm-MIBI SPECT/CT异机融合断层显像,分析显像结果,计算SPECT/CT断层融合显像的摄取比值(UR);依据病理诊断将患者分成肺癌组和良性病变组,以良性病变组UR的x+1s为诊断阈值,评价其对肺癌的诊断效能。结果:45例肺癌患者SPECT断层融合显像的UR为2.56±0.53;20例肺部良性病灶患者UR为1.47±0.42,差异有统计学意义(P<0.05);99Tcm-MIBI SPECT/CT异机融合断层显像对肺癌诊断的灵敏度、特异度和准确度分别为86.67%、85.00%、86.15%;假阳性率和假阴性率分别为15.00%和13.33%;阳性预测值和阴性预测值分别为92.86%和73.91%。结论:99Tcm-MIBI SPECT/CT异机融合断层显像对肺癌诊断有较高的临床价值,为制定治疗方案提供重要依据。更多还原

【Abstract】 Objective:To explore the clinical Value of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the diagnosis of the lung cancer.Methods:Sixty five patients with pulmonary abnormal lesions were chosen for performing different-time 99Tcm-MIBI SPECT/CT fusion imaging.They were divided into lung cancer and benign groups according to the pathologic results.Then the results were analyzed.The uptake ratio(UR) was calculated.Finally the diagnostic efficacy of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the lung cancer was evaluated by the threshold of x+1s of the lung benign group.Results:The UR value of 45 cases in lung cancer group was 2.56 ± 0.53 at the time of 60 min SPECT/CT fusion imaging,while 20 cases of benign group was 1.47 ± 0.42.There was a significant UR difference in two groups(P < 0.05).Using the x + 1s of benign group UR value as a threshold,the diagnostic sensitivity,specificity and accuracy of different-time 99Tcm-MIBI SPECT/CT fusion imaging for the lung cancer was 86.67%,85.00% and 86.15% respectively.The false positive and false negative rate were 15.00% and 13.33%.The positive and negative predictive value were 92.86% and 73.91%.Conclusion:Different-time 99Tcm-MIBI SPECT/CT fusion imaging may be used in the diagnosis of lung cancer with great value and it could provide the important clinical information for clinical treatment planning.更多还原