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女性生殖道黄色瘤样肉芽肿性炎

Xanthogranulomatous inflammation in the female genital tract

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【作者】 张祥盛张磊磊朱玉红王霞于宁

【Author】 ZHANG Xiang-sheng,ZHANG Lei-lei,ZHU Yu-hong,WANG Xia,YU Ning(Department of Patholgy,the Affiliated Hospital,Binzhou Medical Colloge,Binzhou 256603,China)

【机构】 滨州医学院病理学教研室

【摘要】 目的探讨女性生殖道黄色瘤样肉芽肿性炎的病因、临床病理学特征和生物学行为。方法对3例女性生殖道黄色瘤样肉芽肿性炎作了临床病理观察、免疫组化染色,并做了随访。结果3例女性生殖道黄色瘤样肉芽肿性炎1例累及卵巢,1例累及双侧输卵管,1例累及子宫内膜。年龄分别是32、22和62岁。组织学观察显示病灶内大量泡沫状的组织细胞,混有淋巴细胞、浆细胞和少量嗜中性粒细胞浸润,偶见多核巨细胞。免疫组化染色:泡沫细胞CD68阳性,淋巴细胞CD3和CD20阳性,κ、λ阳性。结论女性生殖道黄色瘤样肉芽肿性炎虽是一种罕见的炎性病变,但只要记住它的存在及特点,就可以避免误诊。

【Abstract】 Purpose To study the etiologies and clinical-pathologic features and biological behavior of xanthogranulomatous inflammation in the female genital tract.Methods 3 cases of xanthogranulomatous inflammation in the female genital tract were studied by the clinical and pathological features,immunechemistry-histological stain and clinical follow up.Rusults Described three cases of one affecting endometrium,one affecting the fallopian tube,and one confined to the ovary.The patients was a 37,22 and 62-year-old woman respectively.The histology revealed extensive infiltration of the by foamy histiocytes and a variable amount of inflammatory cells including plasma cells,lymphocytes,and occasional multinucleated giant cells.Immunohistochemistry showed positive staining for C D68 in foamy histiocytes and CD3 and CD20 in the lymphocytes.κ、λ also positive in the lymphocytes.Conclusions Xanthogranulomatous salpingitis is an unusual inflammatory lesion.

  • 【文献出处】 临床与实验病理学杂志 ,Chinese Journal of Clinical and Experimental Pathology , 编辑部邮箱 ,2008年05期
  • 【分类号】R711.3
  • 【被引频次】3
  • 【下载频次】118
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