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盐酸戊乙奎醚治疗急性有机磷中毒临床观察

Study of Penehyclidine Hydrochloride on Acute Organophosphate Poisoning

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【作者】 郑伟华徐华

【Author】 ZHENG Wei-hua, XU Hua Department of Emergency, Zhongshan People′s Hospital of Guandong 528403, China

【机构】 广东省中山市人民医院急诊科

【摘要】 目的:比较盐酸戊乙奎醚(长托宁)与阿托品治疗急性有机磷中毒(AOPP)的疗效。方法:将67例AOPP患者随机分为两组,以阿托品+氯解磷定为对照组(32例),长托宁+氯解磷定为治疗组(35例),比较两组的治疗效果。结果:治疗组中毒症状消失时间、CHE恢复程度、用药总量、治愈时间、反跳率均优于对照组(P<0.05)。结论:长托宁是治疗AOPP较为理想的药物。

【Abstract】 Objective:To compare the efficiency of penehyclidine hydrochloride (changtuoning) and atropine on cases of acute organophosphate poisoning (AOPP). Methods: 67 cases of AOPP were randomly divided into control group(n=32) and therapeutic group(n=35). The control groups were treated with pyraloxime chloride and chantuoning and the therapeutic groups were treated by pyraloxime chloride and atropine. The therapeutic efficiency was compared. Results: The therapeutic groups were better in toxic symptom extinction time, CHE recovery degree, total dosage, curing time and rebound rate than those of control group. Conclusions: Organophosphate poisoning is an ideal medicine to treat AOPP.

  • 【文献出处】 岭南急诊医学杂志 ,Lingnan Journal of Emergency Medicine , 编辑部邮箱 ,2008年03期
  • 【分类号】R595.4
  • 【被引频次】1
  • 【下载频次】47
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