【摘要】 目的了解Maroni公式是否能准确反映我国慢性肾脏病(CKD)患者的每日蛋白质摄入(eDPI)情况。方法选择2006年11月至2007年4月住院的各期CKD患者100例,根据24h尿蛋白排泄量分为A、B、C三组,营养膳食科根据其标准体重、原发病及肾功能分级制订相应的饮食方案,3d后收集其24h尿液标本测定24h尿尿素氮量(UUN),根据Maroni公式,利用24hUUN来估算患者eDPI,并与患者留取尿液标本当日实际营养处方的DPI配对,以验证两者符合率。结果三组CKD患者应用Maroni公式估算的eDPI与其当日实际营养处方的DPI相比,P均>0.05,无显著性差异。结论本研究结果提示24h尿蛋白排泄量不影响应用Maroni公式估算的我国CKD患者eDPI。通过该公式估算的我国各期CKD患者的eDPI与实际营养处方的DPI一致。因此,Maroni公式是适用评估我国CKD患者饮食蛋白质摄入的一种简便、准确的方法。更多还原

【Abstract】 Objective To validate the Maroni’s Formula of estimating protein intake of Chinese patients with chronic kidney disease. Methods From November 2006 to April 2007, 100 cases of the CKD patients were assigned to 3 groups according to their 24 hours urine protein excretion amount: A group, 24 hours urine protein excretion amount > 3.0g/24h ; B group, <3.0g/24h but> 1.0g/24h ; and C group, <1.0g/24h . They were given appropriate diet based on their GFR , and their 24 hours UUN were detected 3 days after to estimate their protein intake by the Maroni’s Formula ,then their eDPI were compared with their prescribed DPI on the same day. Results The eDPIs of A、B、C groups and their prescribed DPIs respectively did not differ statistically by paired analysis(P>0.1)as well as those in the total population of the 100 patients. Conclusion This study suggests that the Maroni’s formula of estimating protein intake is valid to Chinese patients with chronic kidney disease as same as it do to the patients of Occidental country , and there was no difference among the three subgroups.更多还原