【摘要】 目的:探讨影响原发性胆囊癌(pri mary carcinoma of the gallbladder,PCG)患者的预后相关因素。方法:对2004年-2007年诊治27例原发性胆囊癌患者的临床、病理资料进行回顾分析,Kaplan-Meier法比较各组间的生存率,COX比例风险模型分析各因素对预后的影响。结果:单因素分析表明CEA、CA19-9、Nevin分期、治疗方法与PCG患者的预后有关。胆囊癌单纯切除组和根治组与姑息手术组、剖腹探查组、非手术组间有显著差异。COX比例风险模型分析表明CEA、CA19-9、Nevin分期、手术治疗4个因素与PCG生存时间显著相关,其中Nevin分期、手术治疗风险比最高。结论:CEA、CA19-9、Nevin分期、手术方式为PCG患者独立影响因素。更多还原

【Abstract】 Objective:To investigate prognostic factors for primary carcinoma of the gallbladder(PCG).Methods:From 2004 to 2007,23 patients with primary carcinoma of the gallbladder were treated and eligible for the analysis.Kaplan-Meier survival analysis and Cox proportional hazard model were used to analyze the relationship between the prognostic factors and survival time.Results:Kaplan-Meier analysis showed that CEA,CA19-9,Nevin stage,surgical treatment were related to prognosis.Simple and radical resection for gallbladder cancer were statistical difference compared with palliative resection and biopsy(P<0.05).Cox regression model indicated that CEA,CA19-9,Nevin stage,surgical treatment were related to PCG survival time.Conclusion:CEA,CA19-9,Nevin stage,surgical prognosis were independent prognostic factors of PCG patients.更多还原