【摘要】 目的比较非特异性间质性肺炎(NSIP),隐源性机化性肺炎(COP)、脱屑型间质性肺炎(DIP)临床及影像学特征。方法回顾性分析在本院住院治疗并诊断为NSIP,COP,DIP 8例患者的临床、高分辨CT(HRCT)及病理资料。结果8例患者的平均发病年龄为54.5岁,女性较为多见(5例);最常见的症状为咳痰(8例),咳嗽(7例)及气短(7例),velcro啰音在NSIP患者最为多见;NSIP患者主要的HRCT表现为随机分布的磨玻璃样变,以胸膜下分布为主;COP患者则以沿支气管血管束分布的实变为主,可伴有磨玻璃样变;DIP患者主要表现为胸膜下磨玻璃样变。结论NSIP、COP、DIP组患者症状及阳性体征无明显差异,但HRCT的特征性改变可间接反映其病理学特征。更多还原

【Abstract】 Objective To compare the difference of clinical and radiological findings between patients with nonspecific interstitial pneumonia(NSIP),cryptogenic organizing pneumonia(COP),and desquamative interstitial pneumonia(DIP).Methods Case history and high-resolution computed tomography(HRCT),pathological findings of 8 patients with diagnoses of NSIP,COP and DIP hospitalized in the hospital were reviewed.Results The mean age at onset was 54.5 years,and there were more female patients(5 patients).Expectoration(8 patients),cough(7 patients) and dyspnea(7patients) were most common symptoms.Velcro-type crackles were more common in patients with NSIP.The dominant CT pattern exhibited in NSIP patients was ground-glass attenuation with a random,subpleural distribution.The most typically findings in the patients with COP was consolidation with or without ground-glass attenuation with bronchovascular distribution.And in the patients with DIP,subpleural ground-glass attenuation was dominant change.Conclusion There is no significant difference of symptoms and physical signs among the groups,but HRCT has some characteristic findings in accordance with the pathological changes.更多还原