【摘要】 目的应用超声检测心肌梗死患者颈动脉血管结构与缓冲功能的改变。方法超声检查40例心肌梗死患者和30例健康者为对照组的颈动脉,测量颈动脉内-中膜厚度(IMT)、舒张末期内径(Dd)和收缩末期内径(Ds),并测量受检者肱动脉收缩压与舒张压,计算颈动脉弹性系数(Ep)、僵硬度(β)与顺应性(AC)3个参数以评价颈动脉缓冲功能。结果心肌梗死患者颈动脉IMT较对照组增厚,差异有统计学意义(P<0.05);心肌梗死患者颈动脉Ds和Dd较对照组增加,但差异无统计学意义(P>0.05);心肌梗死患者颈动脉Ep和β较对照组增大,差异有统计学意义(P<0.01);心肌梗死患者颈动脉AC较对照组减小,差异有统计学意义(P<0.05)。结论心肌梗死患者颈动脉IMT增厚,Ep和β增大,AC减小;IMT结合Ep、β与AC能更全面反映心肌梗死患者颈动脉结构和功能改变,对临床诊断和治疗方案的选择与评估有重要参考价值。更多还原

【Abstract】 Objective To investigate the structure and function of carotid artery in patients with myocardial infarction with high-frequency ultrasound.Methods The carotid artery of 40 patients with myocardial infarction and 30 normal controls were exam- ined with high-frequency ultrasound.The intima-media thickness(IMT),end-systolic diameter(Ds)and end-diastolic diameter (Dd)were measured with two-dimensional ultrasound.The brachial artery systolic and diastolic pressure were measured to calculate the Ep,βand AC.Results The IMT was thicker in the myocardial infarction subjects than in the control subjects(P<0.05).The Ds and Dd were larger in the myocardial infarction subjects than in the control subjects(P>0.05).The Ep,βwere higher while AC was lower in myocardial infarction subjects than in the control subjects(P<0.05).Conclusion IMT combined with Ep,βand AC can provide the characteristics of structure and function changes of carotid artery.更多还原