【摘要】 目的观察偏侧咀嚼条件下SD大鼠的翼外肌组织学变化。方法30只SD大鼠随机分成实验组(24只)和对照组(6只),实验组分为拔牙组(12只)和分牙组(12只)。6周后将动物处死,对其双侧翼外肌、咬肌进行光镜和透射电镜观察。结果实验组双侧翼外肌和咬肌肌原纤维均有不同程度的细胞与组织损害及改建。翼外肌的损害程度重于咬肌。工作侧和非工作侧没有明显差异。结论偏侧咀嚼可以造成翼外肌的组织学损伤,这种损伤可能是颞下颌关节病的持续因素之一。更多还原

【Abstract】 Objective To study histological changes of lateral pterygoid muscles of SD rats in unilateral mastication.Methods Thirty SD rats were employed to accomplish this study.Twelve of their molars were extracted and other twelve were given the teeth-division.The remaining six rats served as the control group.After six weeks their masseters and lateral pterygoid muscles were excised and observed with light microscope and electronmicroscope.Results Lateral pterygoid muscle fibers suffered from considerable cell and tissue degeneration and reconstruction in experimental groups.The working side was observed to show no significant difference from the non-working side.The injury of lateral pterygoid muscle was more serious than masseter.Conclusion The study demonstrates that unilateral mastication may cause certain injury to pterygoid muscles.However,it cannot be concluded that lateral pterygoid muscle plays a key role in TMD revoking.更多还原