【摘要】 探讨未治疗的妊娠期糖代谢异常是否对孕妇、围生儿有不良影响。选择160名孕妇根据孕24～39周所做75g口服葡萄糖耐量试验结果及治疗情况分为未治疗妊娠期糖代谢异常组(妊娠期糖尿病及妊娠期糖耐量减低,37例),治疗的妊娠期糖尿病组(25例),糖代谢正常者设为对照组(98例)。对这3组孕妇及新生儿妊娠结局进行比较,结果表明,未治疗的妊娠期糖代谢异常组孕妇年龄、体重大于糖代谢正常孕妇(P<0.05),而且子痫前期发生率、剖宫产率、早产、巨大儿发生率显著高于对照组,均具有统计学意义(P<0.05)。未治疗的妊娠期糖代谢异常与早产、巨大儿具有独立相关性。由此可见,未治疗的妊娠期糖代谢异常能增加孕妇和围生儿患病率,应重视其诊断及治疗。更多还原

【Abstract】 This paper evaluates the effect of untreated gestational abnormal glucose metabolism on maternal and fetal outcomes. 160 women of 24～39 weeks of gestation, who had taken 75 g oral glucose tolerance test, were selected and classified into normal glucose tolerance group (n=98), untreated gestational abnormal glucose metabolism (GDM/GIGT) group (n=37), treated gestational diabetes mellitus group (n=25). The results show that the women with untreated abnormal glucose metabolism (GDM/GIGT) were significantly older in age, and more obese than control subjects (P<0.05). The proportions of preeclampsia, cesarean section, preterm birth and macrosomia were significantly higher in untreated GDM/GIGT subjects than normal glucose tolerance subjects (P<0.05). The proportion of preterm birth and macrosomia was independently associated with untreated GDM/GIGT. It is concluded that untreated gestational abnormal glucose metabolism was associated with increased risk of the maternal, fetal outcomes studied.更多还原