Objective To investigate brucine on regulatory role of immune function in mice.Methods The method of Dinitrochlorobenzene induced delayed type hypersensitivity(DTH) in mice was used to observe the effect on ear swelling,thymus index and spleen index.Results Brucine can confront ear swelling by 2,4-Dinitrochlorobenzene(DNCB) induced in mice,and has less effect on the weight of spleen and thymus.The dose-effect relationship of brucine is not manifest.Conclusion Brucine has depressant effect on immune system a...