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4项指标联合检测诊断冠心病的临床价值

Clinical value of combined detection of four items of parameters in the diagnosis of coronary heart disease

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【作者】 林志芳岑丽莲柯尊彬贾冰李海珠帅虎梅敏

【Author】 LIN Zhi-fang, CEN Li-lian, KE Zun-bin, JIA Bing, LI Hai-zhu, SHUAI Hu, MEI Min. Department of Clinical Laboratory, the First People’s Hospital of Zhaoqing City,Zhaoing 526021, China

【机构】 广东省肇庆市第一人民医院检验科广东省肇庆市第一人民医院检验科 526021526021

【摘要】 目的探讨同型半胱氨酸(tHcy)、超敏C反应蛋白(hs-CRP)、脂蛋白(a)[Lp(a)]和D-二聚体(DD)与冠心病的关系。方法检测160例冠心病患者血清tHcy、hs-CRP、Lp(a)和血浆DD水平,并选择健康人群80例作为对照组。结果冠心病患者血清tHcy、hs-CRP、Lp(a)和血浆DD水平显著高于健康对照组(P<0.05)。结论联合检测血清tHcy、hs-CRP、Lp(a)和血浆DD水平的变化,对冠心病的预防和早期诊断及动态监测有着十分重要的临床价值。

【Abstract】 Objective To explore the relationship of four items of parameters including total homocysteine (tHcy), high sensitive C-reactive protein (hs-CRP), lipoprotein (a) [LP (a)],D-dimer (DD) and coronary heart disease.Methods 160 patients with coronary heart disease (CHD) (CHD group) and 80 healthy people (control group) were enrolled in the investigation. The concentrations of serum tHcy, hs-CRP, LP (a) and plasma DD were detected in all subjects.Results The concentrations of serum tHcy, hs-CRP, LP (a) and plasma DD in CHD group were significantly higher than those of control group (P<0.05).Conclusion Combined detection of serum tHcy, hs-CRP, LP (a) and plasma DD has very important clinical value in the prophylaxis, early diagnosis and dynamic monitoring of coronary heart disease.

  • 【文献出处】 检验医学与临床 ,Laboratory Medicine and Clinic , 编辑部邮箱 ,2008年13期
  • 【分类号】R541.4
  • 【被引频次】2
  • 【下载频次】58
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