【摘要】 目的探讨奎硫平治疗老年精神分裂症的疗效、适宜剂量和副反应。方法对57例首发的老年精神分裂症患者给予奎硫平治疗8周,分别在治疗前后的1、2、4、6、8周给予PANSS量表和TESS量表评定。结果奎硫平治疗老年精神分裂症的显效率82.46%,起效时间为2周,有效剂量为200～400mg/d。结论奎硫平对老年精神分裂症的治疗,无论是阴性症状,还是阳性症状,都有肯定的疗效,且起效时间快,副反应少而轻微,有更高的安全性和更好的治疗依从性。更多还原

【Abstract】 Objective To investigate the efficacy and side effects of quetiapine in the treatment of old schizophrenia.Methods 57 old patients with the first-onset schizophrenia were studied for 8 weeks.The efficacy was assessed with PANSS and TESS before and after 1,2,4,6,8 Weeks treatment.Results The significant effective vate was 82.46%.The onset of effect was 2 weeks.The theraputic dose was 200~400mg/d.Conclusion Quetiapine is an ideal antipsychotic druy with rapid onset of effect,few and light side effects,higher safety profile and better conpliance.更多还原