【摘要】 采用高效液相色谱法测定瘟疫消颗粒剂中黄芩苷的含量,以Symmetry C18（3.9mm×150,5μm）为色谱柱,甲醇-0.2%磷酸水溶液（45:55）为流动相,检测波长:280nm;流速:1.0mL·min^-1;柱温:25℃。结果表明黄芩苷在0.0248～0.124mg·mL^-1范围内有良好的线性关系（r=0.9993）,平均回收率为96.93%（RSD=0.92%）。测得瘟疫消颗粒剂中黄芩苷的含量为9.0mg·g^-1。该测定方法简单,专属性强,结果准确,重现性良好,可用于瘟疫消颗粒剂的质量控制。更多还原

【Abstract】 The content of baicalin in Wenyixiao granules was determined by HPLC.The Symmetry C18 (3.9mm×150,5μm) was adopted as chro- matagraphic column,the mobile phase was acetonitrile-0.2% phosphoric acid solution (45:55),the wavelength was 280nm,the velocity of flow was 1.0ml/min and the column temperature was 25℃.The result showed that baicalin had excellent linear relationship between 0.0248～0.124mg/mL (r= 0.9993).The average recovery was 96.93% (RSD=0.92%) and we got the content of baicalin in the Wenyixiao granules was 9.0 mg/g.This method was brief,exclusive,and accurate and had good reproducibility.It could be used to control the quality of Wenyixiao granules.更多还原