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肝动脉化疗栓塞联合深部热疗治疗原发性肝癌的临床研究

Study for Primary Hepatic Carcinoma Treated with Transcatheter Arterial Chemoembolization in Adjuvant with Thermotherapy

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【作者】 柳弥张宁玲李秋梅杨林

【Author】 LIU Mi1,ZHANG Ning-ling1,LI Qiu-mei1,et al.(1.Department of Oncology;2.Department of Radiology.the Affiliated Hospital of North Sichuan Medical College.Nanchong 637000,China)

【机构】 川北医学院附属医院肿瘤科川北医学院附属医院放射科

【摘要】 目的:探讨肝动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)联合深部热疗治疗原发性肝癌(primary hepatic carcinomas,PHCs)的疗效。方法:将42例晚期PHCs随机分为TACE联合深部热疗组(研究组)和单纯TACE(对照组),每组各21例。研究组采用TACE联合深部热疗治疗,于TACE后第1天开始热疗,隔天一次,共3次;对照组采用单纯TACE治疗。对比分析2组肿瘤体积变化及1年生存率。结果:研究组和对照组近期缓解率分别为80.95%和61.90%(P<0.05);1年生存率分别为57.10%和42.80%(P<0.05)。结论:TACE联合深部热疗可以显著提高PHCs的近期疗效和1年生存率。

【Abstract】 Objective:To evaluate the efficacy of transcatheter arterial chemoembolization(TACE)in adjuvant with thermotherapy in the treatment of primary hepatic carcinomas(PHCs).Methods:Forty-two patients with advanced PHCs were randomly divided into two groups(the study group and the control group),21 cases in each.The patients in the study group were treated by TACE in adjuvant with thermotherapy,and the patients in the control group were treated by TACE alone.Results:The short-term remission rate of the study group and control group were 80.95%and 61.90%,respectively(P<0.05).The survival rate of both groups at 1 year were 57.10% and 42.80%,respectively(P<0.05).Conclusion:TACE in adjuvant with thermotherapy might obviously enhance the short-term curative effect primary hepatic carcinoma about 1 year survival rate.

【基金】 四川省教育厅重点项目07ZA030
  • 【文献出处】 华西医学 ,West China Medical Journal , 编辑部邮箱 ,2008年04期
  • 【分类号】R735.7
  • 【被引频次】4
  • 【下载频次】105
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