【摘要】 目的:探讨在卵巢癌肿瘤细胞减灭术中,整块切除盆腔肿瘤与受累之直肠、乙状结肠的可行性、有效性和安全性。方法:对35例原发性卵巢癌患者施行肿瘤细胞减灭术,根据术中发现卵巢肿瘤与直肠、乙状结肠粘连固定,进行整块切除盆腔肿瘤与受累之直肠、乙状结肠。观察手术病灶残留情况,手术时间,术中出血量和术中术后并发症。结果:29例(82.8%)达到满意肿瘤细胞减灭术(残留病灶<1 cm,平均手术时间375 min(185～510 min),估计手术平均出血量650 mL(200～2 100 mL)。1例术中损伤右侧输尿管。术后并发症包括切口感染7例(20%),术后病率5例(14.3%),肠梗阻2例(5.7%)和吻合口瘘1例(2.9%)。结论:作为晚期卵巢癌肿瘤细胞减灭术的一部分,整块切除盆腔肿瘤与受累之直肠、乙状结肠的手术方法是有效、安全、可行的。更多还原

【Abstract】 Objective To study the efficacy and safety of low anterior en bloc resection of the rectosigmoid plus adjacent pelvic tumour as part of cytoreduction for primary ovarian cancer.Methods Thirty-five patients with primary ovarian cancer received an en bloc resection of ovarian tumour and a rectosigmoid resection in cytoreductive surgery depending on the findings during operation.Parameters for safety and efficacy were analyzed as primary statistical endpoints.Results Optimal cytoreduction(residual tumour less than 1 cm) was achieved in 29 patients(82.8%).An injury to the right urete took place during operation.Postoperative complications included 7 case of(20%) of wound complications,5(14.3%) of septicemia,2 of(5.7%) ileus and 1 of(2.9%) anastomotic leak.Conclusion An bloc resection of pelvic tumour and adjacent involved rectosigmoid as part of cytoreduction for ovarian cancer is effective and safe.更多还原