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脑出血急性期患者并高钠血症临床研究
Clinical research on patients with intracerebral hemorrhage complicated hypernatremia during acute period
【摘要】 目的研究脑出血并发高钠血症病人病死率及发生原因。方法收集160例脑出血病人,其中23例并发高钠血症(血清钠离子浓度>145mmol/L)者分入高钠血症组(A组),其余137例不伴高钠血症者归入对照组(B组)。结果A组死亡13例,病死率56.5%;B组死亡29例.病死率21.2%,两者差异有统计学意义(P<0.01)。丘脑出血发生率,高钠血症组明显高于对照组(P<0.05);空腹血糖≥6.1mmol/L,白细胞计数≥10~8/L.血压≥23.9/14.6kPa,体温≥39℃及血肿破入脑室者百分比,高钠血症组均明显高于对照组(P<0.01)。结论脑出血并发高钠血症者病死率明显高于对照组,且血清钠离子水平越高,病死率越高,与糖尿病、丘脑出血、发热、甘露醇使用量大等因素相关。
【Abstract】 Objective To study the mortality and the cause of intracerebral hemorrhage complicated hypernatremia.Methods One hundred and sixty cases of intracerebral hemorrhage were studied,23 cases with hypernatremia as group A and other 137 cases as control group B.Results Thirteen cases died,the mortality was 56.5% in group A,and in group B 29 cases died,the mortality was 21.2%.There was an obvious difference between group A and B(P<0.01).In group A,thalamic hemorrhage,temperature over 39℃,and the amount of mannitol were much more than that in group B(P<0.05)respectively.Conclusion The mortality of pa- tients with intracerebra[hemorrhage complicated hypernatremia is significantly greater than control group.Moreover,the higher of natriumion concentration,the greater of the mortality.The cause of hypernatremia is correlated with diabetes,thalamic hemorrhage, fever,and application of mannitol.
- 【文献出处】 中国实用神经疾病杂志 ,Chinese Journal of Practical Nervous Diseases , 编辑部邮箱 ,2008年08期
- 【分类号】R743.34
- 【被引频次】3
- 【下载频次】100