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脑出血急性期患者并高钠血症临床研究

Clinical research on patients with intracerebral hemorrhage complicated hypernatremia during acute period

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【作者】 杨霄鹏李秋芳杨瑞玲

【Author】 Yang Xiaopeng Li Qiu fang Yang Ruiling Department of Neurology,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China

【机构】 郑州大学第二附属医院神经内科郑州大学护理学院临床教研室河南大学附属东京医院药剂科

【摘要】 目的研究脑出血并发高钠血症病人病死率及发生原因。方法收集160例脑出血病人,其中23例并发高钠血症(血清钠离子浓度>145mmol/L)者分入高钠血症组(A组),其余137例不伴高钠血症者归入对照组(B组)。结果A组死亡13例,病死率56.5%;B组死亡29例.病死率21.2%,两者差异有统计学意义(P<0.01)。丘脑出血发生率,高钠血症组明显高于对照组(P<0.05);空腹血糖≥6.1mmol/L,白细胞计数≥10~8/L.血压≥23.9/14.6kPa,体温≥39℃及血肿破入脑室者百分比,高钠血症组均明显高于对照组(P<0.01)。结论脑出血并发高钠血症者病死率明显高于对照组,且血清钠离子水平越高,病死率越高,与糖尿病、丘脑出血、发热、甘露醇使用量大等因素相关。

【Abstract】 Objective To study the mortality and the cause of intracerebral hemorrhage complicated hypernatremia.Methods One hundred and sixty cases of intracerebral hemorrhage were studied,23 cases with hypernatremia as group A and other 137 cases as control group B.Results Thirteen cases died,the mortality was 56.5% in group A,and in group B 29 cases died,the mortality was 21.2%.There was an obvious difference between group A and B(P<0.01).In group A,thalamic hemorrhage,temperature over 39℃,and the amount of mannitol were much more than that in group B(P<0.05)respectively.Conclusion The mortality of pa- tients with intracerebra[hemorrhage complicated hypernatremia is significantly greater than control group.Moreover,the higher of natriumion concentration,the greater of the mortality.The cause of hypernatremia is correlated with diabetes,thalamic hemorrhage, fever,and application of mannitol.

【关键词】 脑出血高钠血症
【Key words】 Intracerebral hemorrhageHypernatremia
  • 【文献出处】 中国实用神经疾病杂志 ,Chinese Journal of Practical Nervous Diseases , 编辑部邮箱 ,2008年08期
  • 【分类号】R743.34
  • 【被引频次】3
  • 【下载频次】100
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