【摘要】 目的观察糖尿病患者输注麦芽糖后用不同型号血糖仪测定血糖结果的差异,探讨其对临床护理工作的启示。方法将40例糖尿病患者随机分为麦芽糖组和对照组各20例,分别输入10%麦芽糖注射液250ml和0.9%氯化钠注射液250ml,于空腹和输注第1、2、3小时各时点采集静脉血和指尖血分别用日立7600型自动生化分析仪(生化仪法)、GDH-NAD快速血糖仪(氧化酶法)及GDH-PQQ快速血糖仪(脱氢酶法)测定血糖。结果糖尿病患者输注麦芽糖后1h,氧化酶法所测血糖值与生化仪法比较,差异无显著性意义(均P>0.05),第2、3小时显著低于生化仪法(P<0.05,P<0.01),但其值仍高于正常值上限,属安全范畴;糖尿病患者输注麦芽糖后1~3h脱氢酶法测定的血糖值显著高于生化仪法(均P<0.01)。输注0.9%氯化钠注射液后1h氧化酶法和脱氢酶法测定值与生化仪法比较,差异无显著性意义(均P>0.05),而第2、3小时显著低于生化仪法(P<0.05,P<0.01),2种方法所测血糖变化趋势类似。结论糖尿病患者输注麦芽糖后,氧化酶法测量的血糖值较为合理,脱氢酶法测定的血糖值显著偏高,输注麦芽糖者不宜用GDH-PQQ血糖仪进行血糖检测。更多还原

【Abstract】 Objective To investigate the difference in blood glucose changes determined by different types of glucose meters and its impact on the medical care.Methods Forty pateints with diabetes were randomly divided into two groups: In the maltose infusion group, 250 ml 10% maltose was infused, while in the control group, 250 ml normal saline was infused. Blood glucose and finger tip blood glucose concentrations at fasting, and 1st, 2nd and 3rd h since commencement of normal saline and maltose infusion were measured with different types of glucose meters. The difference in bood glucose level determined by different methods was compared.Results Intravenous plasma and capillary blood glucose levels tested by GDH-NAD rapid glucose meter were similar to those determined by auto-biochemical analyzer at 1st h since commencement of maltose infusion (P>0.05 for both), while at 2nd and 3rd h, the blood glucose tested by the former were significantly lower than those tested by the latter (P<0.05,P<0.01), and higher than the maximal limit; the blood glucose levels tested by GDH-PQQ rapid blood glucose meter at 1st, 2nd and 3rd h since maltose infusion were significantly higher than those tested by auto-biochemical analyzer (P<0.01 for all). In the control group, the blood glucose tested by these 3 methods showed no significant differences at the 1st h (P>0.05 for all), while the values tested at 2nd and 3rd h by GDH-NAD and GDH-PQQ glucose meters were significantly lower than those tested by auto-biochemical analyzer (P<0.05,P<0.01), and the trend of blood glucose change was similar.Conclusion Blood glucose concentrations tested by GDH-NAD rapid glucose meter were close to those tested by auto-biochemical analyzer when maltose was infusd in diabetics. However, those tested by GDH-PQQ glucose meters were significantly higher, which suggested that GDH-PQQ rapid glucose meter was not fit for the blood glucose monitoring in patients receiving maltose infusion.更多还原