【摘要】 报道了一种应用原子力显微镜(AFM)实现可控纳米定位沉积的探针修饰新方法。采用改进的AFM探针修饰方法—AFM系统控制的自动进针法—替代通常的将探针浸入"墨水"的直接蘸针法,可控制"墨水"吸附在探针的针尖末端,有效避免纳米点制造过程中非定位沉积的干扰。利用该方法修饰的探针可在DNA分子上可控制备氯化铜溶液纳米点阵,这为生物大分子的局部修饰、加工和改造提供有效途径。更多还原

【Abstract】 In this paper, we present a coating AFM tip method to facilitate the dip-pen nanolithography (DPN) processes. The small amount of ink can be limited to the apex of atomic force microscope (AFM) tip by adjusting AFM operation parameters. With this automatic AFM-engage system overloading ink, usually disturbing imaging and manipulating, can be avoided. Thereby, a uniform nanoarray of CuCl2 is constructed on a DNA molecule. The unique technique may provide a novel approach to precisely modify biological molecule at the nano-meter scale.更多还原