节点文献
基质固相分散-牛奶、蜂蜜中喹诺酮的多残留分析
Matrix Solid-phase Dispersion for Multi-residues Analysis of Quinolones in Milk and Honey
【摘要】 以C18为基质固相分散剂,采用基质固相分散技术进行样品前处理,建立了基质固相萃取-液相色谱法分析牛奶和蜂蜜中4种氟喹诺酮的方法,并对基质固相萃取条件和色谱分离条件进行了探讨和优化.在2.5 ng/g和10.0 ng/g添加水平,4种氟喹诺酮类药物的平均加标回收率为81.9%~111.6%,相对标准偏差<7%.检出限为0.05μg/L.
【Abstract】 A new method for the simultaneous determination of four quinolones in milk and honey was developed by using matrix solid-phase dispersion technology as sample pretreatment followed by liquid chromatography and fluorescence detection.The parameters of matrix solid-phase dispersion and chromatographic separation were investigated and optimized.At the spiked levels of 2.5 ng/g and 10.0 ng/g,the recoveries of the four quinolones were ranged from 81.9% to 111.6% with RSD< 7 %.The detection limit of the method were 0.05 μg/L.
【关键词】 基质固相分散；
喹诺酮；
液相色谱法；
牛奶；
蜂蜜；
【Key words】 matrix solid phase dispersion； quinolones； liquid chromatography； milk； honey；
【Key words】 matrix solid phase dispersion； quinolones； liquid chromatography； milk； honey；
【基金】 教育部博士点学科基金资助项目(20050075003)
- 【文献出处】 河北大学学报(自然科学版) ,Journal of Hebei University(Natural Science Edition) , 编辑部邮箱 ,2008年06期
- 【分类号】TS207.53
- 【被引频次】21
- 【下载频次】276