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超声提取麦冬总黄酮的工艺研究

Study of the ultrasonic extracting technique of total flavonoids from Radix Ophiopogonis

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【作者】 谢明华蔡鑫君陈稀烦

【Author】 XIE Ming-hua1,CHEN Xi-fan2(1.Yuhang Hospital Affiliated to the Medical School of Hangzhou Teachers college,Hangzhou 311100,China;2.The First People’s Hospital of Hangzhou,Hangzhou 310022,China)

【机构】 杭州师范大学医学院附属余杭医院浙江中医药大学药学院杭州市第一人民医院分院

【摘要】 目的优化超声技术提取麦冬总黄酮的工艺条件。方法采用L9(34)正交试验法,考察乙醇浓度、乙醇用量、提取时间、提取次数对超声提取的影响,以总黄酮含量为考核指标,确定最佳提取条件。结果最佳提取工艺为加12倍生药量的60%乙醇,超声提取3次,每次45min。结论此方法是一种简单、快捷、高效、可行的提取。

【Abstract】 OBJECTIVE The conditions of ultrasonic extracting technology of flavonoids from Ophiopogon japonicus were optimized.METHODS The orthogonal design L9(34)was used to explore the factors of ethanol concentration,solvent quantity,ultrasonic time and extraction times influencing the ultrasonic extracting process and determine the optimum conditions.The content of total flavoinds of Ophiopogon japonicus was used as the assessments.RESULTS The results showed that optimum conditions were:12 times weight of Ophiopogon japonicus of 60% ethanol to extract for 45 min for 3 times.CONCLUSION The technique of ultrasonic extracting is a simple,fast,efficient and viable extraction methods.

  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2008年11期
  • 【分类号】TQ461
  • 【被引频次】18
  • 【下载频次】525
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