【摘要】 目的评价咪唑斯汀联合曲尼司特治疗慢性荨麻疹的疗效。方法采用随机开放平行对照的方法,对100例慢性荨麻疹患者进行随机分成治疗组和对照组,患者随机分成两组,治疗组口服咪唑斯汀和曲尼司特,对照组口服咪唑斯汀,观察治疗第14天的疗效及停药1周后的复发率。结果治疗四周后两组有效率分别为:治疗组为96%,对照组为88%,两者之别差异无显著性(x2=2.18,P>0.05)。停药1周后的复发率,治疗组为24.0%,显著低于对照组的46.0%(x2=4.31,P<0.05)。结论咪唑斯汀联合曲尼司特治疗慢性荨麻疹疗效高,复发率低,值行临床推广使用。更多还原

【Abstract】 Objective To evalucate the efficacy of mizolastine combined tranilast in the treatment of chronic urticaria. Methods A randomized, open-label, parallel comparative clinical trial was conducted in 100 patients. They were divided into study group and control group. The patients in study group were treated with mizolastine and tranilast. The recurrent rates were also recorded four week after discontinuation of the treatment. Results The efficant rates of study group and control group were 96.0% and 88.0% respectively. But there was no significantly statistical difference between two groups (x2=2.18. P>0.05). Conclutions Mizolastine combined tranilast have high clinical efficacy and low recurrent rate in the treatment of chronicurticaria.更多还原