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2型糖尿病患者脉压与慢性肾损害

Pulse Pressure and Chronic Kidney Disease in Patients with Type 2 Diabetes

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【作者】 王健王慧珍卢惠茹刘玉芳

【Author】 WANG Jian, WANG Hui-zhen, LU Hui-ru, LIU Yu-fang

【机构】 天津市第一中心医院干部科天津市第一中心医院干部科 天津300192天津300192

【摘要】 目的为了观察2型糖尿病脉压与年龄及蛋白尿的关系;方法选择血肌酐<2.00mg/d1的住院患者,检测收缩压、舒张压、脉压以及24小时尿蛋白定量;结果SBP及PP在微量蛋白尿组和临床蛋白尿组是增加的,在老年组也是如此,而DBP在老年组是下降的趋势。多因素回归分析升高的PP与增加的PP明显相关(p<0.001)。结论在2型糖尿病患者,PP与年龄、蛋白尿程度及大动脉硬化紧密相关。

【Abstract】 Objective To determine the association between both age and degree of albuminuria and pulse pressure in patients with type 2 diabetes. Methods The hospitalized type 2 diabetic patients with serum creatinine <2.00 mg/dl were studied. Systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP) and 24 hours albuminuria was checked. Results SBP and PP were greater in patients with microalbuminuria and clinical albuminuria, as well as in the older groups, whereas DBP tended to be lower in the older age groups. Multiple regression analysis indicated that increased albuminuria was independently associated with greater PP (p<0.001). Conclusions PP is closely associated with higher age, degree of albuminuria, and large artery stiffness in patients with type 2 diabetes.

【关键词】 糖尿病肾病脉压动脉硬化
【Key words】 diabetic nephropathypulse pressurealbuminuria
  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2008年03期
  • 【分类号】R587.2
  • 【被引频次】1
  • 【下载频次】38
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