【摘要】 目的:探讨妊娠期妇女血浆D-二聚体含量的变化。方法:采用ELISA方法测定本院产科门诊和住院部收治妊娠6至41周及产后3d的330例孕产妇(每4孕周一组,每组30例,共11组)血浆D-二聚体含量。结果:随着妊娠的进展孕妇血浆D-二聚体含量逐渐上升,即由(0.311±0.080)mg/L升至(1.796±0.442)mg/L,产后开始下降(P<0.01)。结论:随着妊娠进展,孕产妇血浆D-二聚体含量呈生理性地升高,其测定值不能作为诊断深静脉血栓、肺栓塞和弥漫性血管内凝血的唯一指标。更多还原

【Abstract】 Objective: To explore the change of plasma D-dimer level in pregnant women. Methods: The plasma level of D-dimer was measured with ELISA method in 330 pregnant women registered to the wards or outpatient services of our hospital. These subjects, either within 6 to 41 weeks of pregnancy or 3 days postpartum, were allocated to 11 groups based on their gestational durations with a 4-week increment. Results: The level of D-dimer increased with the progress of pregnancy [from (0.311±0.080) to (1.796±0.442) mg/L] and decreased postpartum (P<0.01). Conclusion: There appears to be a physiological increase in D-dimer level in pregnant women. The observed value of D-dimer should therefore not be used as the unique index for diagnosis of deep venous thrombosis, pulmonary embolism and disseminated intravascular coagulation.更多还原