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苦参总碱对小鼠体内抗肿瘤作用的研究
Experimental Studies on the Anticancer Effect by Alkaloids form Sophora flavescens
【摘要】 研究了苦参总碱的体内抗肿瘤作用。通过苦参总碱对荷S180肉瘤和H22肝癌小鼠的瘤重和生存时间影响的研究,观察了苦参总碱的小鼠体内抗肿瘤作用。结果表明:苦参总碱剂量中生药含量在8g/kg以上能抑制荷S180和H22小鼠瘤体的生长,其抑制率可达30%,从而延长荷瘤小鼠的生存时间,表明苦参总碱具有明显的抗肿瘤作用。
【Abstract】 Antitumor effects of Alkaloids from Sophora flavescens on weight and survival time of S180 and H22 -bearing mice in vitro were studied. The results showed that alkaloids from Sophora flavescens could inhibit the growth of cancer cells of S180-bearing mice and prolong the survival time of H22 -bearing mice.
【关键词】 苦参总碱；
抗肿瘤作用；
荷瘤小鼠；
【Key words】 alkaloids of Sophora flavescens； antitumor effect； tumor-bearing mice；
【Key words】 alkaloids of Sophora flavescens； antitumor effect； tumor-bearing mice；
- 【文献出处】 现代食品科技 ,Modern Food Science and Technology , 编辑部邮箱 ,2008年03期
- 【分类号】R285
- 【被引频次】12
- 【下载频次】363