【摘要】 目的了解重症监护病房(ICU)的细菌耐药状况,并与普通病房相比较,观察两者不同之处,为不同科室临床用药提供参考。方法采用ATB全自动微生物分析仪对阳泉煤业集团总医院2004～2005年分离的ICU常见病原菌进行药物耐药性分析,并与普通病房进行比较。耐药率的显著性比较用χ~2检验。结果ICU的主要致病菌依次为铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌等。在主要的致病菌中,ICU与普通病房分离的肺炎克雷伯菌的耐药率差异有统计学意义(P<0.01)。铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌等两者耐药率差异有统计学意义(P<0.05)。结论ICU病原菌耐药率明显高于普通病房。当感染发生时,应及早做细菌培养及药敏实验,根据药敏结果选择药物,真正做到对症治疗。更多还原

【Abstract】 Objective To investigate the distribution and drug resistance situation of pathogenic bacteria isolated from the intensive care unit(ICU),and compare with the other clinical departments, so as to provide a reference for clinical therapy.Methods ATB fully automatic microorganism analyzer was adopted to perform drug resistance assay for common pathogenic bacteria isolated from the intensive care unit in our hospital from the year of 2004 to 2005.X~2 test was employed to compare the significance of resistance rate difference.Results The three most common isolated pathogenic bacteia were Pseudomonas aeruginosa,Klebsiella pneumoniae and Escherichia coli.There was statistical resistant rate differences between Klebsiella pneumoniae strains isolated from ICU and from general wards(P<0.01),and so were Pseudomonas aeruginosa,Escherichia coli and Staphylococcus aureus(all P<0. 05).Conclusion The resistant rates of pathogenic bacteia isolated from ICU were significantly higher than those isolated from the other clinical departments.Bacterial culture and drug sensitive test should be carried out as soon as possible so as to choose antibacterial drugs according to the drug sensitivity results.更多还原