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恶性淋巴瘤患者乙型肝炎病毒感染状况分析

The analysis of hepatitis B virus infection in Non-Hodgkin lymphoma patients

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【作者】 张祥忠何敏彭爱华童秀珍李娟陈运贤

【Author】 ZHANG Xiang-zhong,HE Min,PENG Ai-hua,TONG Xiu-zhen,LI Juan,CHEN Yun-xian*.Department of Hematology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China

【机构】 中山大学附属第一医院血液内科中山大学附属第一医院血液内科 广东广州510080广东广州510080

【摘要】 目的了解本院初诊非霍奇金淋巴瘤(NHL)患者中乙型肝炎病毒(HBV)的感染状况。方法对163例NHL患者临床资料进行回顾性分析,分析HBV表面抗原(HBsAg)阳性患者的比率。结果本组NHL患者HBsAg阳性率为20.86%,明显高于该地区普通人群(13.28%);20~50岁组患者HBsAg阳性率高于低年龄组。结论NHL患者HBsAg阳性率高于普通人群,HBV感染可能对恶性淋巴瘤的发病有一定的作用。

【Abstract】 Objective To analyze the hepatitis B virus(HBV)infection status of the first diagnosed Non-Hodgkin lymphoma(NHL)patients in our hospital.Methods The hepatitis B virus surface antigen(HBsAg)in 163 NHL patients was detected.The positive rates of HBsAg in the patients and general population were compared.Results The positive rate of HBsAg was significantly higher in NHL patients than that in general population(20.86%vs13.28%,P<0.05).The positive rate in NHL patients aged from 20 to 50 years was significantly higher than that in the younger patients.Conclusion The positive rate of HBsAg in NHL patients is higher than that in general population.HBV infection may play important roles in the development of malignant lymphoma.

  • 【文献出处】 国际内科学杂志 ,International Journal of Internal Medicine , 编辑部邮箱 ,2008年02期
  • 【分类号】R733.1;R512.6
  • 【被引频次】11
  • 【下载频次】183
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