【摘要】 目的:研究肾病综合征型IgM肾病的肾脏病理改变特点。方法:从本院2005～2007年行肾活检诊断为IgM肾病34例中选出临床表现为肾病综合征患者20例。肾组织行光镜HE、PAS、Masson和直接免疫荧光染色,分析其肾脏病理。结果:轻度系膜增生型15例,局灶节段硬化型1例,膜性肾病1例,局灶增生型1例,局灶增生硬化1例,微小病变型1例;并发C3沉积5例,C1q沉积7例。结论:肾病综合征型IgM肾病有其独特的病理表现。更多还原

【Abstract】 Objective:To find out the characteristics of pathology of IgM nephropathy with nephrotic syndrome.Methods: 20 patients with biopsy-proven primary IgM nephropathy who presented with nephrotic syndrome in department of nephrology of our hospital during the period of 2005～2007 were studied.All biopsies were processed for light,immunofluorescence.Results:Renal pathological investigation showed mesangial proliferative glomerulonephritis(MEPGN) in 15 cases(75%),focal and segmental glomerulosclerosis was found in 1 case(5%),membrance glomerulonephritis in 1 case(5%).C3 staining was observed in 25% of specimens with a intensity.Conclusions: Primary IgM nephropathy who presented with nephrotic syndrome is common,the pathology chang is characteristics.更多还原