【摘要】 应用电喷雾多级串联质谱技术对传统中药甘遂根中的弱极性部分化学成分进行了分析鉴定,根据串联质谱数据,共鉴定出39个化合物.其中包括9个新化合物:分别为3-O-(2,3-二甲基丁酰基)-13,20-O-双十二烷酰基巨大戟萜醇(1)、3-O-(2,3-二甲基丁酰基)-13-O-癸酰基-20-O-十六烷酰基巨大戟萜醇(2)、3-O-(2,3-二甲基丁酰基)-13-O-十二烷酰基-20-O-[(9Z,12Z)-十八烷-9,12-二烯酰基]巨大戟萜醇(3)、3-O-(2,3-二甲基丁酰基)-13-O-十二烷酰基-20-O-(十八烷-9Z-烯酰基)巨大戟萜醇(4)、甘遂素I(5)、甘遂素J(6)、甘遂素K(7)、甘遂素L(8)和甘遂素M(9).更多还原

【Abstract】 Acording to the characteristic fragment ions,39 chemical constituents from the weak polar part of the roots of Euphorbia kansui were identified by ESI-MS/MS technique.Among them,9 new compounds were identified as 3-O-(2,3-dimethylbutanoyl)-13-O-dodecanoyl-20-O-dodecanoyl ingenol(1),3-O-(2,3-dime-thylbutanoyl)-13-O-decanoyl-20-O-hexadecanoylingenol(2),3-O-(2,3-dimethylbutanoyl)-13-O-dodecanoyl-20-O-[(9Z,12Z)octadeca-9,12-dienoyl] ingenol(3),3-O-(2,3-dimethylbutanoyl)-13-O-dodecanoyl-20-O-(octadeca-9Z-en-oyl) ingenol(4),kansuinin I(5),kansuinin J(6),kansuinin K(7),kansuinin L(8),and kansuinin M(9).更多还原