【摘要】 在乙醇和水的混合溶液中,将N,N′-二(邻氧乙酸)苄叉丙二胺(1)与氯化铜反应,获得配合物Cu(Ⅱ)L1.H2O.0.25CH3CH2OH(2)[L1=N,N′-二(邻氧乙酸)苄叉丙二胺];当将反应混合溶液的pH值调至8~9,获得Cu(Ⅱ)ClL2.3H2O(3)[L2=N-(邻氧乙酸)苄叉丙二胺];将N,N′-二(邻氧乙酸)苄叉丙二胺(1)与氯化镍反应,获得配合物Ni(Ⅱ)L1.2.75H2O(4).用元素分析、1H NMR和IR谱等方法对所合成的化合物1和配合物2~4进行了表征,并测定了配合物2~4的晶体结构.在配合物2中,铜原子为六配位[CuN2O4],在配合物3中,铜原子为六配位[CuN2O3Cl],在配合物4中,镍原子为六配位[NiN2O4],三个配合物均为畸变八面体结构.抑菌活性大小的顺序:配合物3>配合物2>化合物1.更多还原

【Abstract】 Complex Cu(Ⅱ)L1·H2O·0.25CH3CH2OH(2) [L1=N,N′-bis(o-oxy-acetate) benzylpro-pylenediamine(1)] was synthesized via the reactions between compound 1 and Cu(Ⅱ) dichloride in the solvents of water and ethanol,and Cu(Ⅱ)ClL2·3H2O(3) [L2=N-(o-oxy-acetate) benzylpropylenediamine ] was prepared via the reaction between compound 1 and Cu(Ⅱ) dichloride in the solvents of water and ethanol(pH=8~9).Complex Ni(Ⅱ)L1·2.75H2O(4) was also synthesized by the reactions between the compounds 1 and Ni(Ⅱ) dichloride in water.Compounds 1—4 were characterized by elemental analysis,1H NMR,FTIR spectroscopy and single crystal X-ray diffraction analysis.There are one molecule(hostmolecule),one water molecule(guestmolecule) and quarter ethanol molecule in one asymmetric unit of complex 2,the Cu(Ⅱ) atom exhibits a distorted octahedral geometry.There are one molecule(hostmolecule) and three water molecules in each unit of complex 3,the Cu(Ⅱ) atom exhibits a distorted octahedral geometry.In the asymmetric unit of complex 4,the Ni(Ⅱ) atom also exhibits a distorted octahedral geometry.Complexes 2 and 3 exhibit good antibacterial properties,while the antibacterial properties decrease in the following order: complex 3>complex 2> compound 1.更多还原