【摘要】 以O-马来酸酐化N-邻苯二甲酰化壳聚糖(MPCS)为中间产物,通过γ射线引发,在均相溶液体系制备含有改性壳聚糖-聚丙烯酸的两性凝胶。用红外光谱证实了接枝反应的发生。同时还系统地研究了接枝反应的影响因素,结果表明,接枝率依赖于单体浓度和所用的剂量。通过研究了接枝产物在不同pH值缓冲溶液中溶胀度的变化,结果发现,接枝产物在酸性条件(Ph<7)下溶胀较小,在碱性条件(pH>7)下溶胀度较大。而且还测试了接枝产物在DMF溶剂中的溶胀情况。更多还原

【Abstract】 Poly (acrylic acid)-modified chitosan amphiphilic gels were prepared via O-maleoyl-N-phthaloyl-chitosan as an intermediate by grafting with poly (acrylic acid). The reaction was carried out in a homogeneous sys-tem by γ-ray irradiation. Evidence of grafting was obtained from FTIR spectroscopy. The effects for grafting reaction were investigated systematically. Results show that the grafting degree depends on monomer concentration and ab-sorbed dose. The swelling behavior of chitosan samples with different grafting degree was studied in different buffers as a function of pH. It can be found that all the samples swollen slightly at low pH but very well at high pH. More-over, the swelling behavior of chitosan samples in DMF has been evaluated.更多还原