【摘要】 建立了用气相色谱-氮磷检测器(GC-NPD)测定药物中水合肼的新方法。其萃取和衍生采用同一种试剂-丙酮,一步完成,可简单快速地定量检测药物中水合肼的残留量,其检出限为41.0μg/kg;相对标准偏差小于4.1%;回收率在101.5%~107.8%。已用于药物中水合肼的残留量分析。更多还原

【Abstract】 A rapid and simple method has been developed for the determination of hydrazine in drugs using acetone as a derivative reagent and an extractant to quantitatively extracts and convert hydrazine to from a stable derivative in a single step.The derivatives in the acetone solution was analyzed by gas chromatography with a nitrogen-phosphorus detector(GC-NPD).The detection limit was 41.0 μg/kg,the relative standard deviation was less than 4.1%,and the recoveries were in the range of 101.5%～107.8%.This method has been applied to the determination of hydrazine in drugs.更多还原