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已停跳供心原位心脏移植体外循环管理的探讨

Management of extracorporeal circulation in cardiac arrest orthotopic heart transplantation:Report of 47 cases

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【作者】 杨国锋陈道中陈良万黄雪珊吴锡阶廖崇先

【Author】 Yang Guofeng,Chen Daozhong,Chen Liangwan,Huang Xueshan,Wu Xijie,Liao Chongxian.Department of Cardiac Surgery,Union Hospital,Fujian Medical University,Fuzhou 350001,China

【机构】 福建医科大学附属协和医院心外科

【摘要】 目的探讨已停跳供心原位心脏移植体外循环管理的方法和经验。方法47例终末期心脏病患者采用升主动脉及上、下腔静脉插管;采用中度低温(鼻咽温28.1~29℃),轻-中度血液稀释(血红蛋白82~119g/L),60~90ml/(kg.min)的流量进行体外循环灌注;供心保护方法:先采用1000ml8℃的HTK液首次直接灌注心脏,供心切下后,将供心放到套有无菌塑料袋的无菌器皿中继续将剩余量的4℃HTK液灌完,流出的HTK液可用来浸泡供心。结果47例均顺利脱离体外循环机,术后康复出院。结论合理的灌注技术及良好的心肌保护,可使已停跳供心的原位心脏移植获得成功。

【Abstract】 Objective To study the methods and experience of cardiac arrest orthotopic heart transplantation extracorporeal circulation management.Methods Forty-seven cases of patients with end-stage heart disease applied ascending aorta,and vena cava intubation;the requirement of extracorporeal circulation perfusion:moderate use of low-temperature(nasopharyngeal temperature 28.1~29℃),light-moderate hemodilution(hemoglobin 82~119 g/L),60~90 ml(kg·min);Methods for heart protection:First the heart was perfused with 100 ml of 8℃ directly,then it was cut and put into a sterile container which was covered with a sterile plastic bag,and continued to be perfused with the remaining 4℃ HTK.Finally,the heart was soaked with the outflowing HTK.Results Forty-seven patients were successfully from the CPB machine,after recovered and were discharged.Conclusion Reasonable infusion of technology and good myocardial protection is successful for cardiac arrest orthotopic heart transplantation.

【基金】 教育部优秀青年教师基金资助,基金号:教人司[2003]355
  • 【文献出处】 福建医药杂志 ,Fujian Medical Journal , 编辑部邮箱 ,2008年06期
  • 【分类号】R654.2
  • 【下载频次】39
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