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已停跳供心原位心脏移植体外循环管理的探讨
Management of extracorporeal circulation in cardiac arrest orthotopic heart transplantation:Report of 47 cases
【摘要】 目的探讨已停跳供心原位心脏移植体外循环管理的方法和经验。方法47例终末期心脏病患者采用升主动脉及上、下腔静脉插管;采用中度低温(鼻咽温28.1~29℃),轻-中度血液稀释(血红蛋白82~119g/L),60~90ml/(kg.min)的流量进行体外循环灌注;供心保护方法:先采用1000ml8℃的HTK液首次直接灌注心脏,供心切下后,将供心放到套有无菌塑料袋的无菌器皿中继续将剩余量的4℃HTK液灌完,流出的HTK液可用来浸泡供心。结果47例均顺利脱离体外循环机,术后康复出院。结论合理的灌注技术及良好的心肌保护,可使已停跳供心的原位心脏移植获得成功。
【Abstract】 Objective To study the methods and experience of cardiac arrest orthotopic heart transplantation extracorporeal circulation management.Methods Forty-seven cases of patients with end-stage heart disease applied ascending aorta,and vena cava intubation;the requirement of extracorporeal circulation perfusion:moderate use of low-temperature(nasopharyngeal temperature 28.1~29℃),light-moderate hemodilution(hemoglobin 82~119 g/L),60~90 ml(kg·min);Methods for heart protection:First the heart was perfused with 100 ml of 8℃ directly,then it was cut and put into a sterile container which was covered with a sterile plastic bag,and continued to be perfused with the remaining 4℃ HTK.Finally,the heart was soaked with the outflowing HTK.Results Forty-seven patients were successfully from the CPB machine,after recovered and were discharged.Conclusion Reasonable infusion of technology and good myocardial protection is successful for cardiac arrest orthotopic heart transplantation.
【Key words】 Heart transplant; Donnor heart protection; Extracorporeal circulation;
- 【文献出处】 福建医药杂志 ,Fujian Medical Journal , 编辑部邮箱 ,2008年06期
- 【分类号】R654.2
- 【下载频次】39