【摘要】 目的建立20~40周胎儿胼胝体各径线正常参考值。方法应用二维超声测量621例孕20~40周正常单胎胎儿胼胝体长度、宽度及厚度,与孕周(GA)进行相关回归分析比较。结果胎儿胼胝体各径线超声测量值与GA呈正相关(长度r=0.802,P<0.001;宽度r=0.724,P<0.01;厚度r=0.701,P<0.01);胼胝体各径线随GA增长的最适方程为二次曲线方程[长度(mm)=-60.437+5.2073(GA)-0.0652(GA),P<0.001;宽度(mm)=0.2863+0.2555(GA)-0.0014(GA),P<0.001;厚度(mm)=-1.4780+0.1944(GA)-0.0023(GA),P<0.001]。结论胎儿胼胝体各径线与孕周呈正相关。不同孕周胎儿胼胝体径线正常参考值将为产前判断胼胝体发育不全、准确估计孕周提供参考数据。更多还原

【Abstract】 Objective To construct reference ranges for normal Chinese fetal corpus callosum dimensions from 20 to 40 weeks’ gestation.Methods The lengths,widths,and thicknesses of the corpus callosum were measured using 2D ultrasonography in 621 normal fetuses between 20 and 40 weeks of gestation,and the correlations and regressions between dimension and gestational age(GA) were calculated.Results Each dimension of the fetal corpus callosum was positively correlated with GA(r =0.802 for length,P<0.001;r =0.724 for width,P<0.01;r = 0.701 for thickness,P<0.01).Corpus callosum growth curve is best fit by a quadratic function:length(mm)=-60.437+5.2073(GA)-0.0652(GA)2,P<0.001;width(mm)=0.2863+0.2555(GA)-0.0014(GA)2,P<0.001;thickness(mm)=-1.4780+0.1944(GA)-0.0023(GA)2,P<0.001.Conclusions Sizes of the corpus callosum in normal fetuses are positively correlaled with the gestation age.Normative measurements of the fetal corpus callosum from this study may serve as a useful reference in assessing the agenesis of corpus callosum or dating of GA.更多还原