【摘要】 目的:观察注射用牛肺表面活性剂预防早产儿呼吸窘迫综合征的临床疗效。方法:将54例胎龄28～32周早产儿随机分成两组,预防组在对照组治疗基础上经气管给予注射用牛肺表面活性剂100 mg/kg,比较两组发生呼吸窘迫综合征情况和病死率。结果:预防组呼吸窘迫综合征发生率25.0%、病死率7.1%,对照组呼吸窘迫综合征发生率61.5%、病死率34.5%,二组比较差异有统计学意义(P<0.05)。结论:早产儿生后预防性应用注射用牛肺表面活性剂可降低早产儿呼吸窘迫综合征的发生率和病死率。更多还原

【Abstract】 Objective:To study the efficacy of calf pulmonary surfactant for injection in prevention of respiratory distress syndrome (RDS) of premature infants.Methods:Fifty-four premature infants of gestational age of 28～32 weeks were divided into a prevention group and a control group.The prevention group adopted 100 mg/kg of calf pulmonary surfactant for injection through trachea in addition to measures taken in the control group.Comparison of ineidenee of P,DS incidence and mortality was made between the two groups.Results:RDS incidence and mortality were 25.0% and 7.1% in the prevention group and were 61.5% and 34.5% in the control group.There was a significant difference (P<0.05).Conclusions :The prophylactic treatment with calf pulmonary surfactant for premature infants can reduce the incidence and death rate of RDS.更多还原