【摘要】 目的评价晚期选择性PCI对老年心肌梗死患者左室功能的作用。方法对45例老年首次心肌梗死患者,平均于发病后(3.9±2.2)周行冠状动脉造影,并进行前瞻性研究。按梗死相关冠状动脉是否进行PCI分为两组:PCI组:25例,为平均于(4.9±3.1)周行成功PCI患者;对照组:20例,为未行PCI患者。对PCI组患者,于术前平均(4.6±3.2)d及术后随访期平均(6.8±2.3)个月及对照组患者于相当于PCI组术前和随访期时间进行12导联心电图和心脏超声检查,以评价心电图QRS积分、左室容量、收缩及舒张功能的改变。结果PCI组术后随访期左室容量较术前减小、QRS积分减低,左室收缩功能明显改善,而左室舒张功能无明显变化。与对照组相比,PCI组随访期左室容量较小,而收缩及舒张功能明显好于对照组。结论对老年心肌梗死患者,晚期选择性PCI能阻止左室重构,改善患者的远期左室功能,对临床明显有益。更多还原

【Abstract】 Objective To assess the impact of late elective percutaneous coronary intervention(PCI) on left ventricular(LV) function in elderly patients with myocardial infarction.Methods forty-five patients with fist-times myocardial infarction,were prospectively studied and divided into two groups.Group I included 25 patients who underwent successful PCI((4.9±3.1)weeks after myocardial infarction),and group II comprised 20 patients who had not undergone PCI.In both groups,serial echocardiographic examinations and electrocardiogram were performed before and during follow up to assess the changes in QRS score,LV volumes,systolic and diastolic function.Results During follow-up,LV volumes and QRS score were decreased,and systolic function was improved after PCI,but LV diastolic function remain unchanged.But compared with control group,LV volumes of the PCI group was smaller,LV systolic and diastolic function were better than the control group.Conclusion The late elective PCI may significantly improve functional status of the elderly patients with myocardial infarction.更多还原