【摘要】 目的:设计和制作一种被动式旋流混合器,为药品分析和生物制剂提供新选择。方法:从层流扩散混合机理出发,设计利用流体自身旋转提高混合效益的被动式旋流微混合器。提出了聚甲基丙烯酸甲酯(PMMA)旋流式微混合器的一种简易制作方法,并从理论上分析了在超纯水环境中紧固方法实现微混合器基片和盖板之间封合的可行性。结果:采用体试显微镜和表面轮廓仪对制作的旋流式微混合器形貌、混合腔深度及加工表面粗糙度进行了表征。结论:在一定尺度范围内随混合腔深度的增加,混合器混合性能得到改善,微混合器可以作为生物制剂和药品分析的新选择。更多还原

【Abstract】 Objective;to design and produce a passive vortex mixer,to provide a new choice for drug analysis and biological agent. Methods;on the base of diffusion theory during laminar flow,a passive vortex micromixer with higher mixing efficiency by fluids themselves rotation in the mixer is designed.A simplified fabrication technology for the polymethyimethacrylate micromixer was introduced.Without adhesive,the whole process of the seal can be realized by screw fixation in ultra-pure water,and this way could be explained in theory.Results;the depth of mixing chamber,machined surface roughness and appearance of micromixer were characterized by stereomicroscope with CCD and surface profilometer.Conclusions;with the increase of micromixer depths, the mixing efficiency is also improved.更多还原