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高性能多孔β-TCP陶瓷/明胶复合材料制备研究
Preparation of High Performance Porous β-Tricalcium Phosphate/Gel Scaffold
【摘要】 采用Ca(OH)2/H3PO4中和反应,超声分散条件下制备β-TCP粉末原料;通过致孔剂方法制备多孔β-TCP支架,并在β-TCP成型过程中加入K2HPO4提高支架强度;将制备的多孔支架与明胶复合,冷冻干燥后与戊二醛交联,得到多孔β-TCP/明胶复合支架。实验表明,加入K2HPO4后提高了支架强度,当多孔β-TCP支架孔隙率为49.47%时抗压强度为7.60 MPa。多孔β-TCP支架的孔隙率高、强度高、孔隙大小可控、孔隙连通性好;进一步与明胶复合后,制备的多孔β-TCP/明胶复合材料,符合组织工程结构特征的要求。
【Abstract】 Pure P-TCP powders were prepared from Ca(OH)2/H3PO4 in the ultrasonic field.The powders were added with K2HPO4 and mixed with porogens as the stearic acid.The porousβ-TCP scaffolds were mixed with gelatin and cross-linked with glutaraldehyde.The compressive strength of the porousβ-TCP scaffold by the addition of K2HPO4 was increased.The composite of porosity 49.47%has the compressive strength of 7.60 MPa.The pores in theβ-TCP scaffolds were homogeneous and interconnected,and theβ-TCP/Gel composite scaffold was close to bones in its composition and structures.
- 【文献出处】 稀有金属材料与工程 ,Rare Metal Materials and Engineering , 编辑部邮箱 ,2008年S1期
- 【分类号】TB333
- 【被引频次】6
- 【下载频次】114