【摘要】 采用高效液相色谱法测定了变温动物(鱼、蛙、鳖)和恒温动物(鸡、狗、牛)脑和脊髓中多巴胺(DA)和5-羟色胺(5-HT)的含量。结果表明:(1)变温动物和恒温动物脑和脊髓中DA和5-HT含量存在较大差异。变温动物脑和脊髓中DA含量分别为(0.228±0.014)μg/g和(0.155±0.003)μg/g,5-HT含量分别为(0.465±0.139)μg/g和(0.104±0.004)μg/g;恒温动物脑和脊髓中DA含量分别为(0.258±0.015)μg/g和(0.236±0.018)μg/g;脑和脊髓中5-HT为(1.020±0.166)μg/g和(0.712±0.344)μg/g。(2)湖泊与池塘的鲢脑中DA含量分别为(0.197±0.018)μg/g和(0.073±0.012)μg/g,血液中肾上腺素(Ad)含量分别为(0.065±0.013)μg/g和(0.025±0.007)μg/g。这说明DA和Ad在鱼类环境应激中有重要作用。(3)从鱼类经鸟类到哺乳类纵向比较,其神经递质的含量是不同的。以进化论和全息论的观点来看,其中可能蕴藏着生物医药潜力。更多还原

【Abstract】 The dopamine (DA) and 5-hydroxyindoleaceti (5-HT) in coldblooded (fish,frogs,turtles) and warmblooded (hens,dogs,cows) was measured in high performance liquid chromatography. The results showed as follows:(1) DA of coldblooded in brain and spinal were (0.228±0.014) μg/g,(0.155±0.003) μg/g,respectively. 5-HT of coldblooded in brain and spinal were (0.465±0.139) μg/g,(0.104±0.004) μg/g,respectively. DA of warmblooded in brain and spinal were (0.258±0.015) μg/g,(0.236±0.018) μg/g,respectively. 5-HT of warmblooded in brain and spinal were (1.020±0.166) μg/g,(0.712±0.344) μg/g,respectively. (2) DA and adrenalin (Ad) of siver carp in the lake and pond showed that the contents of them were different which proved that DA and Ad played a great role in environment stress-response of fishes. (3) The vertical comparison of the neurotransmitter from the fishes,through the bird,and to the mammal showed that its content was different. According to the biological evolution and hologram theory,perhaps in their central nervous system could contain potential biological medicine.更多还原