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运脾方不同剂量对脾虚大鼠耐力作用的研究

Study on Effect of Yun-Pi Prescription in Different Doses on Endurance of Rats with Splenic Asthenia

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【作者】 崔利萍孙远岭周纬奚政君杨珍

【Author】 Cui Liping,Sun Yuanling,Zhou Wei,et al Shanghai Children Medical Center(200127)

【机构】 上海交通大学医学院附属新华医院、上海儿童医学中心

【摘要】 [目的]观察运脾方不同剂量对脾虚大鼠的耐力作用,探索治疗儿童厌食症的有效方药运脾方临床治疗效果的作用机理。[方法]通过建立利血平致脾虚动物模型,设立正常组、模型组、阳性对照组(消食健儿糖浆组),运脾方大剂量组、中剂量组、小剂量组,测定大鼠体重变化、食量消耗,以及测定游泳时间观察其对大鼠耐力的影响。[结果]运脾方能使脾虚大鼠的食量和体重明显增加的同时,延长了脾虚大鼠的游泳时间。[结论]运脾方能够有效地抗疲劳及改善脾虚大鼠耐力,对脾虚大鼠有明显的治疗作用。

【Abstract】 [Objective] To observe the effects of Yun-Pi Prescription of different doss on endurance of rats with splenic asthenia and to explore the mechanism of Yun-pi Prescription in treatment of children apositia.[Methods] To set up the animal model of splenic asthenia with reserpine.Experimental rats were randomly divided into six groups:the control group,the model group,the positive control group.Xiao Shi Jian Er Syrup,and Yun-Pi Prescription treatment groups including high,middle and low dose.Changes of body weight,food intake and swimming time were measured to determine the endurance of rats.[Results] Yun-Pi Prescription could increase body weight and food intake,prolong the swimming time of splenic asthenia rats.[Conclusion] Yun-Pi Prescription could effectively counteract fatigue and improve endurance of rats with splenic asthenia and it is useful in treatment rats with splenic asthenia.

【基金】 国家中医药管理局课题(No:DZX016A)~~
  • 【文献出处】 浙江中医药大学学报 ,Journal of Zhejiang University of Traditional Chinese Medicine , 编辑部邮箱 ,2008年04期
  • 【分类号】R285.5
  • 【被引频次】3
  • 【下载频次】95
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