【摘要】 [目的]研制白簕消炎喷雾剂,为开发利用白簕资源提供依据。[方法]分别提取白簕、野菊花、车前草中的黄酮,通过正交试验检测3种物质提取物的混合杀菌效果,研制一种具有快速消炎、镇痛、杀菌等作用的喷雾剂。[结果]白簕、野菊花、车前草中的总黄酮含量分别为:3.54%、3.41%、3.45%。配方为40 mg/ml白簕提取物、30 mg/ml野菊花提取物、2 mg/ml车前草提取物的喷雾剂0.5 h后的杀菌效果较好,但仍剩余43.3%的菌体,1.0 h后的杀菌效果最好,适合作外用药。配方为60 mg/ml白簕提取物、60 mg/ml野菊花提取物、4 mg/ml车前草提取物的喷雾剂3.0 h后的杀菌效果较好,有效抑制了细菌再生,仅剩余16.7%的菌体。[结论]利用白簕、野菊花和车前草的黄酮提取物,可制成绝佳的消炎杀菌喷雾剂。更多还原

【Abstract】 [Objective] The study was to develop the antiphlogistic spray with Acanthopanax trifoliatus(L.) Merr and provide the basis for the development and utilization of A.trifoliatus resource.[Method] The flavonoids in A.trifoliatus,Chrysanthemum indicum L.and Plantain were extracted.The mixed sterilization effect of the extracts of 3 kinds of materials was detected through orthogonal test,and a spray with rapid antiphlogistic,analgesia and sterilization effect was developed.[Result] The total flavonoids contents in A.trifoliatus,C.indicum and Plantain were 3.54%,3.41% and 3.45% resp.When the formula of the spray was A.trifoliatus extracts of 40 mg/ml,C.indicum extracts of 30 mg/ml and Plantain extracts of 2 mg/ml,its sterilization effect after useing for 0.5 h was better,but there still 43.3% thalli were remained.The spray’s sterilization effect after using for 1.0 h was the best and it suitable to being used as the external drugs.When the formula of the spray was A.trifoliatus extracts of 60 mg/ml,C.indicum extracts of 60 mg/ml and Plantain extracts of 4 mg/ml,its sterilization effect after useing for 3.0 h was better,and it effectively inhibited the bacteria regrowth,there only 16.7% thalli were remained.[Conclusion] With flavonoid extracts from A.trifoliatus,C.indicum and Plantain,the superexcellent antiphlogosis and sterilization spray could be made.更多还原