【摘要】 目的研究相位敏感方法应用于T1定量测量的可行性及意义。方法采用相位敏感方法消除相位误差,保存反转恢复序列中磁化矢量的极性。再根据恢复后的图像数据的实部计算得到T1值图像。结果采用快自旋回波反转恢复序列得到了一组混合加权的幅度及相位图像,对其进行相位敏感校正后再做非线性最小二乘拟合,得到了体模的T1值及人体膝关节的T1图像。结论通过相位敏感方法保留极性信息的T1定量测量,在反转恢复序列成像中是可行的,并且具有较好的精确度。更多还原

【Abstract】 Objective To research on the feasibility and significance of the phase sensitive method in quantitive T1 meas-urement .Methods The phase sensitive method was used to remove the phase errors and restore the polarity of theinversionrecovery data . Thenthe T1 values were calculated by the real part of the complex datain polarity restoredi mages .Results Aseries of magnitude and phase i mages were collected by FSE-IRsequence ,and the polarityinformation was restored usingthe phase sensitive method . T1 values of phantoms and T1-map of a volunteer’ s knee were obtained by least square fitting .Conclusion The phase sensitive method is feasible for polarity restoration in T1 mapping using IR sequence ,and it showsgood accuracy .更多还原