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氯诺昔康复合丙泊酚、芬太尼用于人工流产的止痛疗效研究
Effects of Lornoxicam Combined with Propofol and Fentanyl on Induced Abortion
【摘要】 目的:观察氯诺昔康复合丙泊酚、芬太尼用于无痛人工流产的临床效果。方法:随机将600例早期妊娠妇女分成氯诺昔康组(L组)300例和对照组(P组)300例。麻醉前2h,L组口服氯诺昔康8mg,P组服用安慰剂。观察记录两组麻醉诱导时间、苏醒时间、麻醉用药总量、术后腹痛发生情况和不良反应。结果:术后腹痛L组少于P组(P<0.01),术中丙泊酚用药量L组少于P组(P<0.05)。结论:氯诺昔康用于无痛人工流产可增强麻醉效果,减少丙泊酚用量,减少术后腹痛的发生率。
【Abstract】 Objective:To assess the analgesic effect of lornoxicam combined with propofol and fentanyl for the induced abortion period.Method:A randomized,placebo-controlled clinical study were enrolled six hundred women who were terminated the early pregnancy,and divided into lornoxicam group(300 cases)and placebo group(300 cases)randomly.The L group took lornoxicam 8 mg and P group took placebo at 2 hours before surgery.The induction and recovery time of post anesthesia,the quantity of anesthesiadrugs postoperative abdominal pain and incidence of adverse events were observed.Result:Lornoxicam-treated patients administered less quantity of propefol and experienced less abdominal pain compared with the placebo patients(P<0.01).Conclusion:Combination of lornoxicam to propofol and fentanyl provides more powerful anesthetic effects in the termination of early pregnancy,and decrease the in- cidence of post-operative abdominal pain.
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2007年12期
- 【分类号】R614;R169.4
- 【下载频次】10