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痛风方剂颗粒镇痛抗炎作用的实验研究

Effects of Tongfeng Granules on Analgesis and Anti-inflammation

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【作者】 徐玉红李东万于军李玉珍陈晓凯

【Author】 Xu Yuhong Li Yuzhen Chen Xiaokai (Affiliated Futian people’s Hospital,Guangdong medical College,Shenzhen,518033 China); Li Dong Wan Yujun (Department of Clinical Pharmacy,Shenzhen People’s Hospital,Second medical college of Jinan University)

【机构】 广东医学院附属福田人民医院暨南大学第二临床医学院深圳市人民医院临床药学研究室广东医学院附属福田人民医院 广东深圳 518033广东深圳 518033

【摘要】 目的:观察痛风方剂颗粒的镇痛、抗炎作用。方法:采用小鼠冰醋酸扭体法和热板法,小鼠二甲苯耳廓肿胀法和角叉菜胶大鼠足跖肿胀法观察痛风方剂颗粒的镇痛、抗炎作用。结果:痛风方剂颗粒对热板所致的小鼠疼痛和醋酸所致的小鼠扭体反应均有显著抑制作用;并能对抗二甲苯所致的小鼠耳廓肿胀和角叉菜胶所致的大鼠足跖肿胀。结论:痛风方剂颗粒具有镇痛、抗炎作用。

【Abstract】 Objective:To evaluate the effects of tongfeng granules on analgesia and anti-inflammation.Method:Writhing test and hot plate test were used for analgesic experiments.Anti-inflammatory effects were investigated in mice with xylene-induced auricular swelling and in rat with edema of hind paw induced by injection of carrageenin.Result:The pains caused by physical and chemical fac- tors were restrained and acute inflammation were inhibited in model animals.Conclusion:Tongfeng granules is effective on analgesia and anti-inflammation.

【基金】 深圳市科技计划(医疗卫生类)项目(项目编号:200405080)
  • 【分类号】R285
  • 【被引频次】12
  • 【下载频次】157
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