【摘要】 目的:研究复方黄根对小鼠急性肝损伤的保护作用。方法:采用四氯化碳、D-氨基半乳糖盐酸盐诱导小鼠急性肝损伤模型,观察复方黄根对小鼠血清ALT、AST活性及肝组织匀浆SOD、MDA、GSH-PX水平的影响,并观察肝组织病理学改变。结果:复方黄根可明显降低小鼠血清中ALT、AST活性,同时能减少肝匀浆MDA含量,并能使降低的肝匀浆SOD、GSH-PX活性升高。结论:复方黄根有明显的保肝作用,其保肝作用与抗脂质过氧化有关。更多还原

【Abstract】 Objective:To investigate the protective effect of Compound HuangGen on acute liver injury in mice.Methods:The models of hepatic damage of acute were induced by CCL4,D-GalN.The ALT,AST level in serum and MDA content,SOD,GSH-PX activites in liver homogenate,Pathology of liver were observed.Results:Compound HuangGen was found to significantly decrease the serum transaminase activities,Meanwhile Compound HuangGen also decreased MDA content and prevented the reduction of SOD,GSH-PX activities in liver homogenate.Conclusion: Compound HuangGen show significant protective action on acute liver injury in mice.更多还原