【摘要】 目的为确定大鼠丘脑腹后外侧核是否也发生触觉信息的会聚,本文研究了大鼠丘脑腹后外侧核神经元触觉反应的特性。方法采用在体细胞外单位放电记录技术,记录麻醉状态下大鼠丘脑腹后外侧核触觉神经元的放电活动。结果在记录的156个神经元中,140个神经元(89.7%)具有单一、连续的小感受野,16个神经元(10.3%)具有两个不连续的感受野。部分神经元对作用于感受野不同部位的相同触觉刺激产生不同的放电形式。此外,还观察到4.5%触觉神经元(n=7),它们仅对感受野内的运动性触觉刺激敏感,而对点状触觉刺激不敏感。结论以上结果表明,在大鼠丘脑腹后外侧核,大多数神经元具有皮肤感受器的时空和模式特性,而少数神经元表现出不同外周感受器相互作用的反应。由此可见,大鼠丘脑腹后外侧核中存在触觉信息的会聚。更多还原

【Abstract】 Objective To determine whether the convergences of tactile information also occur at thalamic ventroposterolateral nucleus in rats,we investigated the properties of tactile responses of the thalamic ventroposterolateral nucleus in rats.Methods Unit responses were recorded extracellularly from thalamic ventroposterolateral nucleus in anesthetized rats.Results Among 156 neurons examined,140 neurons(89.7%)had the single,continual and small receptive fields,and 16 neurons(10.3%)had two discrete receptive fields.Some neurons exhibited different responses to the same intensity stimulation which delivered to different points in their receptive fields.In addition,4.5% neurons(n=7) responded only to locomotive stimulation but not to a punctiform tactile stimulation.Conclusion The majority of neurons in ventroposterolateral nucleus of rats have the spatial,temporal and submodal characteristics of cutaneous receptors, while the minority of neurons exhibit the responses of interaction of different peripheral receptors.Therefore,it is con- cluded that there are convergences of tactile intbrmation at the ventroposterolateral nucleus of rats.更多还原