【摘要】 目的了解猕猴、鼠、旱獭、鸽子、鸡、鱼、蟾蜍血清中抗-HEV抗体流行情况。方法应用双抗原夹心酶联免疫法检测猕猴、鼠、旱獭、鸽子、鸡、鱼和蟾蜍血清中抗-HEV抗体。结果总抗-HEV抗体阳性率为14.41%(113/784)。7种动物中猕猴血清抗-HEV抗体阳性率为7.26%(9/124);鼠和旱獭抗-HEV抗体阳性率分别为34.91%(59/169)和4.74%(9/190);鱼和蟾蜍分别为17.33%(13/75)和25.56%(23/90);鸡和鸽子血清中未检测到抗-HEV抗体。结论猕猴、鼠、旱獭、鱼和蟾蜍中存在HEV感染,鼠抗-HEV抗体阳性率最高;其次为蟾蜍和鱼;鸡和鸽子中未检测到抗-HEV抗体。更多还原

【Abstract】 To investigate the epidemiology of hepatitis E virus(HEV)infection in macaques,rats,marmots,pigeons,chickens,fish and toads.The anti-HEV antibodies in sera of these animals were detected by using a double-antigen sandwich enzyme immunoassay(DS-ELISA).Of 784 sera collected from these animals,113 were anti-HEV positive,with a positive rate of 14.41 %.The positive rates in sera of macaques,rats,marmots,fish,toads were 7.26%(9/124),34.91%(59/169),4.74%(9/190),17.33%(13/75)and 25.56%(23/90),respectively,while antibody was not detected in sera of pigeons and chickens.These results suggest that macaques,rats,marmots,fish and toads could be infected with HEV,and the highest prevalence rate of anti-HEV was found in rats.更多还原