【摘要】 目的探讨恶性综合征(neuroleptic malignant syndrome,NMS)的临床特点与预后,提高临床工作者对本综合征的认识。方法对17例NMS患者进行临床评价。结果①17患者均有肌强直、高热、肌酸激酶值增高;②发病3 d内确诊者8例,全部存活;1周内未得到确诊者3例,全部死亡。结论NMS以肌强直、发热、肌酸激酶值增高为主要特征;避免误诊、早诊断早治疗是改善预后的关键所在。更多还原

【Abstract】 Objective To study the clinical features and prognosis of neuroleptic malignant syn- drome(NMS)in order to improve clinical workers’ understanding of NMS.Method 17 NMS patients were assessed.Result①All the 17 patients had the manifestation of hyperthermia,muscle rigidity and increased CK level;②8 patients were correctly diagnosed within the 3 days after the onset and survived; the 3 patients who did not get a correct diagnosis during the first week died.Conclusion NMS is mainly characterized by muscle rigidity,hyperthermia and increased CK level;avoiding misdiagnosis,early diag- nosis and immediate treatment are the key of better prognosis.更多还原