【摘要】 目的探讨中国城市居民中高脂血症与慢性肾脏病（CKD）的关系。方法对健康体检人员中随机抽取800人进行调查,测定血压、身高、体质量,测定尿白蛋白和尿肌酐、血清肌酐、血总胆固醇、甘油三酯、高密度脂蛋白胆固醇,依血清肌酐计算肾小球滤过率（eGFR）.计算尿白蛋白和尿肌酐比值（ACR）,以eCFR<60 ml·min^-1·1.73m^-2或ACR>30 mg/g并持续3个月。结果查出238名高血脂患者,总患病率29.75%,高血脂患者与正常人群比较,肾损害的发生率分别为15.13%和9.07%,高血脂有/无肥胖的患者,肾损害的发生率分别为19.69%和9.91%。结论高脂血症是发生CKD的重要病因。更多还原

【Abstract】 Objective To explore the urban population hyperlipidemia and chronic kidney disease relationship by epidemiological studies.Methods 800 health examiners were randomly investigation.To determine these blood pressure,height,weight;to determine these urinary albumin and creatinine in urine,serum creatinine,serum total cholesterol,triglyceride,high-density lipoprotein cholesterol.To calculate glomerular filtration rate and urinary albu- min and creatinine ratio according to serum creatinine.Diagnastic criteria of CKD was eGFR<60 ml·min^-1·1.72m^-2and ACR>30mg/g and lasted three months or more.Results 238 patients with high blood lipids was found,the overall prevalence rate was 29.75 %,patients with high blood lipids compared with the normal popula- tion.the incidence of renal injury rates were respectively 15.13 % and 9.07 %.Kidney damage rates were respective- ly 19.69% and 9.91% in the hypercholesterolemia with and without obese patients.Conclusion Hyperlipidemia has become particularly important etiology of CKD.更多还原