【摘要】 目的利用林州市人群为基础的食管癌和胃癌发病登记报告资料,描述性分析林州市居民的食管癌和胃癌发生水平及变化趋势,为该地区的癌症防治研究及效果评价提供有效的参考数据。方法从林州市肿瘤登记处抽取1988年至2003年间登记报告的食管癌和胃癌发生的全部记录,按性别、年龄、年份分组后,与相应的人口数据连接。计算食管癌和胃癌各个年份发病率及世界人口年龄调整率。采用Jionpoint模型获得年龄调整发病率的年度变化百分比(APC),以评价林州市食管癌及胃癌发病率的时间变化趋势。结果2003年林州市人群食管癌和胃癌年龄调整发病率分别为81.78/10万和77.08/10万。1988年至2003年间,两种癌症的年龄调整发病率均呈下降趋势,发病率的EAPC分别为-2.6%和-1.8%,EAPC指标均有统计学意义(P<0.05)。同时,男女性胃癌不同解剖部位(贲门、其他胃)和男女性食管癌合并贲门癌的发病率也呈下降趋势。结论观察期间,林州市人群食管癌和胃癌的发病率呈现下降趋势。随着当地社会经济的发展,居民生活水平的逐步提高,居住环境条件及生活习惯的不断改善,这种下降趋势将会延续。更多还原

【Abstract】 Objective To analyze the incidence and time trends of esophageal and gastric cancers in Linzhou city bassed on the data of Linxian Tumor Registry, and to provide valid reference data for research and effective estimation of cancer control in this area. Methods All incidence records for the both cancers during 1988-2003 were drawn from Linzhou Tumor Registry and grouped by sex, age, year and then linked to corresponding population data. The incidence rates of those two topographic site cancers were calculated and the age-adjusted rates were calculated by direct standardization to the world population. A joinpoint model was used to get the annual percentage change (APC) of the age-adjusted rates, and to estimate the epidemiological trends of both cancers in population of Linzhou city. Results In the year 2003 the age-adjusted incidence rates of esophageal and gastric cancers were 81. 78 per 100 000 and 77. 08 per 100 000, respectively, in the population of Linzhou city. The incidence rate of both cancers showed a decreasing trend from 1988 to 2003. The APC of the incidence rates of esophageal cancer was -2. 6% and that of gastric cancer was - 1. 8%, and both indexes were statistically significant ( P < 0. 05 ). Conclusion The incidence rates of esophageal and gastric cancers have presented a decreasing trends in the population of Linzhou city. This trend will continue along with the development of social economy, elevation of living standard and improvement in living habit and environment.更多还原