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慢性肝病、肝硬化并发感染性休克临床分析

Chronic Hepatitis and Cirrhosis Complicated with Septic Shock:A Clinical Analysis

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【作者】 江宇刘刚龚玲金益辉张友才陈永平

【Author】 JIANG Yu,LIU Gang,GONG Ling,JIN Yi-hui,ZHANG You-cai,CHEN Yong-ping (The First Affiliated Hospital,Wenzhou Medical College,Wenzhou,Zhejiang 325000,China)

【机构】 温州医学院附属第一医院温州医学院附属第一医院 浙江温州325000浙江温州325000

【摘要】 目的探讨慢性肝病、肝硬化并发感染性休克患者临床特征及预后转归情况。方法回顾性分析2002年1月-2005年8月,医院收治的45例慢性肝病、肝硬化并发感染性休克患者临床资料,采用SPSS13.0进行统计学分析。结果45例慢性肝病、肝硬化患者中原发感染为腹腔及肠道感染18例(40.0%);并发急慢性肝功能衰竭30例(66.7%);分泌物培养常见病原菌依次为大肠埃希菌(31.6%)、葡萄球菌属(23.7%)、假单胞菌属(18.4%)、假丝酵母菌属(10.5%)、弧菌属(7.9%)。结论慢性肝病、肝硬化感染性休克原发感染以腹腔及肠道感染为主,病原菌分析革兰阴性菌比例增大,一旦发生感染性休克,极易并发急慢性肝衰竭至死亡。

【Abstract】 OBJECTIVE To study the clinical characteristics and prognosis of chronic hepatitis and cirrhosis complicated with septic shock.METHODS Forty-five cases with chronic hepatitis and cirrhosis complicated with septic shock were observed.SPSS software was used for statistical analysis.RESULTS The infected sites were abdominal cavity and intestinal tract(66.7%) in 45 cases.Thirty cases complicated with hepatic failure were found.Escherichia coli rated the first(31.6%),followed by Staphylococcus(23.7%),Pseudomonas(18.4%),Candida(10.5%),and Vibrio(7.9%) in secretion analysis.CONCLUSIONS The sites easiest to be attacked with infection are abdominal cavity and intestinal tract in these patients.The rate of Gram-negative bacilli is increasing.In these patients acute and acute-to-chronic hepatic failure are common.The death rate is high in these patients.

【关键词】 感染性休克肝硬化肝衰竭
【Key words】 Septic shockCirrhosisHepatic failure
  • 【文献出处】 中华医院感染学杂志 ,Chinese Journal of Nosocomiology , 编辑部邮箱 ,2007年11期
  • 【分类号】R575
  • 【被引频次】2
  • 【下载频次】164
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